Natrelle ® silicone gel-filled Breast Implants Oregon are one of the most studied FDA approved medical devices in existence. There have been hundreds of peer-reviewed studies and published reports involving silicone gel-filled Breast Implants Oregon, including robust epidemiological studies supporting their use. The Institute of Medicine of the National Academies (IOM), concluded in its landmark report (IOM, 1999) that “a review of the toxicology studies of silicones and other substances known to be in Breast Implants Oregon does not provide a basis for health concerns.” More information about the safety of silicone gel-filled implants can be found in the IOM report at .